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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Physical & Chemical properties

Water solubility

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Description of key information

Water solubility at 25°C: 23 g/L .

Key value for chemical safety assessment

Water solubility:
23 g/L
at the temperature of:
25 °C

Additional information

In The CRC Handbook of Chemistry and Physics, a water solubility of 23 g/L is tabulated for leucine.

Furhtermore, the water solubility was also calculated by EpiSuite's WSKOW model.

The suitability of the model was assessed and it was concluded that L-leucine is considered to be inside the applicability domain of the EpiSuite WSKOW model.

The water solubility of L-leucine was estimated to be 21.5 g/L at 25°C. This result shows a good match with the experimentaly determined value.