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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated (Japanese) For justification of read across please refer to section 13.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Analysis of acute toxicity (LD50-value) of organic chemicals to mammals by solubility parameter (delta). 1. Acute oral toxicity to rats
Author:
Nishimura H, Saito S, Kishida F and Matsuo M
Year:
1994
Bibliographic source:
Sangyo Igaku, 36(5), 314-323
Reference Type:
secondary source
Title:
No information
Author:
RIFM
Year:
2009
Bibliographic source:
RIFM database

Materials and methods

Principles of method if other than guideline:
LD50 listed in a QSAR study
Test type:
other: no data
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentan-1-ol
EC Number:
200-752-1
EC Name:
Pentan-1-ol
Cas Number:
71-41-0
Molecular formula:
C5H12O
IUPAC Name:
pentan-1-ol

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: no data
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 200 mg/kg bw

Applicant's summary and conclusion