Registration Dossier
Registration Dossier
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EC number: 265-807-4 | CAS number: 65520-46-9
Endpoint summary
Administrative data
Description of key information
Additional information
According to their molecular structures, substances in the category are expected to hydrolyze into 2 molecules of alcohol and a molecule of adipic acid. Adipic acid is not expected to further hydrolyze because of the absence of hydrolysable groups. Also alcohols esterified with adipic acid do not have hydrolysable groups, therefore no further hydrolysis is expected. This is also confirmed by the predicted half-life of the category members, which is very high (years).
Despite the high stability in the environment, all substances, for which experimental data are available, are readily biodegradable, with the exception of Ditridecyl Adipate, which reaches 57-60% of degradation in 28 days.
It should be considered, moreover, that all category members are quite insoluble, therefore aquatic compartment is not expected to be the main environmental destination of these molecules. Indeed, according to the predicted log KOW and KOC values, these substances are expected to have a quite low mobility in sediments and soil.
According to available vapour pressure data, category members are not expected to go into the atmosphere.
Experimental and predicted values indicate that bioaccumulation potential is low among members of this category. Moreover, toxicokinetics evidence indicates that, once absorbed, diesters of adipic acid are expected to be readily metabolised and excreted.
Also hydrolysis products of the members of this category are expected to have a low bioaccumulation potential, due to the fact that adipic acid is expected to be readily metabolized by living organisms and alcohols representing the side chains of these category members are expected to have a similar behaviour once absorber.
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