Registration Dossier
Registration Dossier
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EC number: 265-807-4 | CAS number: 65520-46-9
Endpoint summary
Administrative data
Description of key information
Basing on a category read-across approach, bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl]adipate is neither irritant to the skin nor to the eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation / corrosion, other
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Adipic acid diesters category. See attached report.
- Remarks on result:
- no indication of irritation
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Adipic acid diesters category members showed no to slight dermal irritation in in vivo studies.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation, other
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Adipic acid diesters category. See attached report.
- Remarks on result:
- no indication of irritation
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Available data on rabbits indicate that category members are not irritant to the eyes.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Basing on the available data, bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl]adipate is classified neither for skin irritation/corrosion nor for serious eye damage/eye irritation according to Regulation (EC) n. 1272/2008.
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
