Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Basing on a category read-across approach, bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl]adipate is neither irritant to the skin nor to the eye.

Key value for chemical safety assessment

Skin irritation / corrosion

Link to relevant study records
Reference
Endpoint:
skin irritation / corrosion, other
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
Adipic acid diesters category. See attached report.
Remarks on result:
no indication of irritation
Interpretation of results:
GHS criteria not met
Conclusions:
Adipic acid diesters category members showed no to slight dermal irritation in in vivo studies.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation, other
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
Adipic acid diesters category. See attached report.
Remarks on result:
no indication of irritation
Interpretation of results:
GHS criteria not met
Conclusions:
Available data on rabbits indicate that category members are not irritant to the eyes.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Basing on the available data, bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl]adipate is classified neither for skin irritation/corrosion nor for serious eye damage/eye irritation according to Regulation (EC) n. 1272/2008.

Categories Display