Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 931-319-1 | CAS number: -
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- publication
- Title:
- Cardiorespiratory changes following chemical applications to gut serosa.
- Author:
- Radhakrishnan et al
- Year:
- 1 985
- Bibliographic source:
- J Auton Nerv Syst, 14(4):363-75
Materials and methods
- Type of study / information:
- other
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
Results and discussion
Any other information on results incl. tables
Application of 0.2-0.3 ml of 0.5% sodium hydroxide to gastrointestinal serosa produced a fall in blood pressure and inhibition of respiration in hypertensive as well as normotensive rats. In 6 (8%) of the animals studied, a fall in heart rate was also seen which was blocked by atropine.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
