Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

No data is available for the registered substance, 2-(ethylthio)ethanol. A bacterial mutagenicity study is, however, available for the related substance, 2,2'-dithiobisethanol (CAS number 1892-29-1), which is a close structural analogue of 2 -(ethylthio)ethanol. It is considered appropriate to read across the results for 2,2'-dithiobisethanol because both are hydroxysulfides containing similar functional groups.

Short description of key information:
In vitro
Gene mutation (Bacterial reverse mutation assay / Ames test): read-across from related substance 2,2'-dithiobisethanol (CAS number 1892-29-1): negative with and without activation in all strains tested (similar to OECD TG 471)

Endpoint Conclusion:

Justification for classification or non-classification

There is evidence for lack of genotoxicity in bacterial cells for the related substance, 2,2'-dithiobisethanol, but studies on mammalian cells are not available and no data are available from testing in vivo. It is therefore not possible to reach a conclusion on genetic toxicity for the registered substance, 2 -(ethylthio)ethanol. In vivo testing is not proposed as the substance is a strictly controlled intermediate so exposure is not expected.