Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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EC number: 205-299-3 | CAS number: 137-51-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 137-51-9
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database; DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: modelling database
- Principles of method if other than guideline:
- Skin irritation (Severe vs mild). Multicase model
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-aminobenzene-1,3-disulphonic acid
- EC Number:
- 205-299-3
- EC Name:
- 4-aminobenzene-1,3-disulphonic acid
- Cas Number:
- 137-51-9
- Molecular formula:
- C6H7NO6S2
- IUPAC Name:
- 4-aminobenzene-1,3-disulfonic acid
- Details on test material:
- - Name of test material : 4-aminobenzene-1,3-disulphonic acid
- Substance type: organic
- Physical state: solid
Constituent 1
Test animals
- Species:
- other: no data
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- no data
- Remarks on result:
- other: Non-irritating
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- 4-aminobenzene-1,3-disulphonic acid gives negative result i.e. not irritating to skin as estimated by the Multicase model from Danish QSAR .
- Executive summary:
4-aminobenzene-1,3-disulphonic acid gives negative result i.e. not irritating to skin as estimated by the Multicase model from Danish QSAR .
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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