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Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 137-51-9
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database; DK-EPA

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: modelling database
Principles of method if other than guideline:
Skin irritation (Severe vs mild). Multicase model
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-aminobenzene-1,3-disulphonic acid
EC Number:
205-299-3
EC Name:
4-aminobenzene-1,3-disulphonic acid
Cas Number:
137-51-9
Molecular formula:
C6H7NO6S2
IUPAC Name:
4-aminobenzene-1,3-disulphonic acid
Details on test material:
- Name of test material : 4-aminobenzene-1,3-disulphonic acid
- Substance type: organic
- Physical state: solid

Test animals

Species:
other: no data
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Reversibility:
no data
Remarks on result:
other: Non-irritating

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
4-aminobenzene-1,3-disulphonic acid gives negative result i.e. not irritating to skin as estimated by the Multicase model from Danish QSAR .
Executive summary:

4-aminobenzene-1,3-disulphonic acid gives negative result i.e. not irritating to skin as estimated by the Multicase model from Danish QSAR .