1,3-di-o-tolylguanidine

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2010-2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)

Deviations:

no

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

Laser scattering/diffraction

Type of particle tested:

primary particle

Type of distribution:

volumetric distribution

Specific details on test material used for the study:

- Name of test material (as cited in study report): DOTG C -oiled grad
- Substance type: organic
- Physical state: solid
- Analytical purity:> 97% see COA
- additive :1-2% oil
- Impurities (identity and concentrations): see COA
- Purity test date: 08/11/2010 and 21/01/2011
- Lot/batch No.: 10111460738 and 11011461153
- Expiration date of the lot/batch: 7/11/2012 and 20/01/2013
- Stability under test conditions: 2 years
- Storage condition of test material: closed in a plastic bag

Percentile:

D50

Mean:

ca. 33 µm

Remarks on result:

other: D(4,3)(migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)

Percentile:

D10

Mean:

ca. 7.19 µm

St. dev.:

1.52

Remarks on result:

other: measured on 2 different batches

Percentile:

D90

Mean:

ca. 66.91 µm

St. dev.:

4.63

Remarks on result:

other: measured on 2 different batches

No.:

#1

Size:

> 10 µm

Distribution:

ca. 14.86 %

Remarks on result:

other: measured on 2 different batches

No.:

#2

Size:

> 60 µm

Distribution:

ca. 86.86 %

Remarks on result:

other: measured on 2 different batches

Mean values are listed in the table below. The samples are different in granulometry.

Batch number	obscuration	D(0,1)	D(4,3)	D(0.9)	D<10 um	D < 60 um	span
10111460738	23,49	7,73	32,35	61,98	12,81	89,01	0,13
	17,11	9,06	33,89	64,24	11,18	87,68	0,14
11011461153	15,96	5,64	32,15	69,35	18,71	86,07	0,11
	15,87	6,33	33,88	72,05	16,74	84,66	0,10
Medium value	18,11	7,19	33,07	66,91	14,86	86,86	0,12
St deviation	3,63	1,52	0,95	4,61	3,47	1,89	0,02
		21,17%	2,87%	6,89%	23,34%	2,18%

 

Conclusions:

The mean particle size, number in volume, of DOTG C test item, is determined to be 33 µm, with 10% of particles presenting a diameter less than 7µm, and 10% of particles presenting a diameter larger than 67µm.

Executive summary:

A study was performed in order to investigate the particle size distribution (granulometry) on 2 batchs of the test substance oiled DOTG C (1,3 -di-tolylguanidine). The study was conducted according to ISO 13320- 1 “International standard for Laser Diffraction Measurements – Principles of Laser diffraction” and in accordance with OECD Test Guideline 110. The mean particle size, number in volume, of DOTG C test item, is determined to be 33 µm, with 10% of particles presenting a diameter less than 7µm, and 10% of particles presenting a diameter larger than 67µm.

Description of key information

The mean particle size, number in volume, of DOTG C test item, is determined to be 33 µm, with 10% of particles presenting a diameter less than 7µm, and 10% of particles presenting a diameter larger than 67µm.

Additional information

A study was performed at Laboratoire Qualité & Soutien Exploitation de MLPC International to investigate the particle size distribution (granulometry) on 2 batchs of the test substance EKALAND DOTG C (1,3 -di-tolylguanidine). The study was conducted according to ISO 13320- 1 “International standard for Laser Diffraction Measurements – Principles of Laser diffraction” and in accordance with OECD Test Guideline 110. The mean particle size, number in volume, of DOTG C test item, is determined to be 33 µm, with 10% of particles presenting a diameter less than 7µm, and 10% of particles presenting a diameter larger than 67µm.