Registration Dossier
Registration Dossier
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EC number: 202-577-6 | CAS number: 97-39-2
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 56.8 µg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 71.9 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 5.68 µg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 2.23 mg/L
- Assessment factor:
- 10
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 25.4 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 2.54 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 5.04 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
According to CLP regulation EC 1272/2008 and the results mentioned hereafter, 1,3-di-o-tolylguanidine should be considered aquatic chronic 3 (H412).
* Short term Toxicity to Fish: 96h-LC50 = 19.3 mg/L
* Short term toxicity to aquatic invertebrates: 48h-EC50 = 7.19 mg/L.
* Toxicity to aquatic algae: 72h-ErC50 = 7.2 mg/L
* Chronic toxicity to fish: no data
* Chronic toxicity to aquatic invertebrates: 21d-NOEC = 2.84 mg/L
* Chronic toxicity to aquatic algae: 72h-EC10 = 4.8 mg/L
* 1,3-di-o-tolylguanidine has an octanol water partition coefficient of 2.9
* 1,3-di-o-tolylguanidine is not readily biodegradable
* 1,3 -di-o-tolylguanidine is hydrolytically stable
1,3-di-o-tolylguanidine is considered H412 on the basis of its non rapid biodegradability and the acute toxicity to fish result.
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