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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Title:
No information
Author:
Anonymous
Year:
2011
Bibliographic source:
OECD Toolbox v2.0, November 2010
Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
Merck KGaA data sheet

Materials and methods

Test guideline
Guideline:
other: read across (grouping: skin irritation inclusion rules by BfR-ketones)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Aluminium tris(2,4-pentanedionato-O,O')
EC Number:
237-741-6
EC Name:
Aluminium tris(2,4-pentanedionato-O,O')
Cas Number:
13963-57-0
Molecular formula:
C15H21AlO6
IUPAC Name:
aluminum tris(4-oxopent-2-en-2-olate)

Results and discussion

In vivo

Results
Irritation parameter:
primary dermal irritation index (PDII)
Basis:
mean
Score:
1.73
Max. score:
8

Any other information on results incl. tables

See attached OECD Toolbox v2.0 study for skin irritation/corrosion.

Note that v3.1 gave identical results.

Applicant's summary and conclusion

Interpretation of results:
irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Classification Xi;R38 (DSD) respectively Skin irritant cateory 2 with H315 (CLP)

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