Registration Dossier
Registration Dossier
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EC number: 237-741-6 | CAS number: 13963-57-0
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro cytogenicity / chromosome aberration study in mammalian cells
- Remarks:
- Type of genotoxicity: chromosome aberration
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 013
- Bibliographic source:
- OECD Toolbox v3.1 (2013)
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 473 (In Vitro Mammalian Chromosome Aberration Test)
- GLP compliance:
- not specified
- Type of assay:
- in vitro mammalian chromosome aberration test
Test material
- Reference substance name:
- Aluminium tris(2,4-pentanedionato-O,O')
- EC Number:
- 237-741-6
- EC Name:
- Aluminium tris(2,4-pentanedionato-O,O')
- Cas Number:
- 13963-57-0
- Molecular formula:
- C15H21AlO6
- IUPAC Name:
- aluminium tris(2,4-pentanedionato-O,O')
Constituent 1
Method
Species / strain
- Species / strain / cell type:
- Chinese hamster lung fibroblasts (V79)
- Metabolic activation:
- with and without
- Metabolic activation system:
- S9
Results and discussion
Test results
- Species / strain:
- Chinese hamster lung fibroblasts (V79)
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Remarks:
- 85.7% negative
- Cytotoxicity / choice of top concentrations:
- not specified
Applicant's summary and conclusion
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