Registration Dossier
Registration Dossier
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EC number: 457-320-2 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48-hour EL50 for Daphnia was 50 mg/L (nominal loading rate)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 50 mg/L
Additional information
One study of the short-term toxicity of EC# 457-320-2 to aquatic invertebrates is available: an acute Daphnia study conducted to GLP and in accordance with OECD Test Guideline 202. Due to the poor water solubility of the test substance, test waters were prepared as Water Accomodated Fractions (WAFs) of nominal loading rates of 0, 42, 93, 203, 452 and 1,000 mg/L. In the absence of a suitable analytical method, test mixtures were analysed for total organic carbon (TOC), but not for test material.
The 48-h EL50 was 50 mg/litre (95% confidence interval 38 to 62 mg/litre); the 48-h LOELR was 42 mg/litre (nominal). The lowest concentration causing 100% immobilisation was 203 mg/litre. TOC concentrations were similar in all test mixtures and the control (0.2-0.3 mg/litre).
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