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Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The NOELR in a 21-day Daphnia reproduction study was 100 mg/L (nominal loading rate).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Additional information

One long-term toxicity to aquatic invertebrates study is available: a 21-day Daphnia reproduction study, conducted in accordance with GLP and OECD Test Guideline 211. Due to the poor water solubility of the test substance, test waters were prepared as water accomodated fractions (WAFs) of the test substance at nominal loading rates of 0, 0.954, 3.05, 9.77, 31.3 and 100 mg/litre. Concentrations of the test material itself were not quantified but total organic carbon (TOC) analysis was employed.

No 21-day EL50 could be determined since there were no statistically significant differences in any of the endpoints measured at any concentration. The NOELR was 100 mg/litre (nominal), the highest loading rate tested. TOC concentrations were similar in all test mixtures and the control (1.4-1.7 mg/litre).