Registration Dossier
Registration Dossier
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EC number: 221-486-2 | CAS number: 3115-49-9
Endpoint summary
Administrative data
Description of key information
Additional information
Fish
Two studies on the short-term toxicity to fish are available, the key study (CIBA-GEIGY, 1985) with a warmwater fish (zebrafish) and the supporting study (CIBA-GEIGY, 1978) with four coldwater fish (rainbow trout, carp, catfish and bluegill).
The 96 hour acute toxicity to zebrafish (Danio rerio) was assessed under static conditions. The calculated 96 hour LC50 based on mortality was 9 mg/L. Therefore, the test item is acutely toxic to fish.
Aquatic invertebrates
Daphnia magna were exposed to the test item for 48 hours under static conditions (Institute of Industrial organic Chemistry Branch Pszczyna, 2012). The 48 hour EC50 was determined to be 0.88 mg/L. Therefore, the test item is acutely very toxic to aquatic invertebrates.
Algae
Cultures of Pseudokirchneriella subcapitata were exposed to the test item under static conditions in accordance with the OECD guideline 201 (2006) (Institute of Industrial organic Chemistry Branch Pszczyna, 2012).
The inhibition of algae growth rate resulted in a ErC50 (72 h) of 27.21 mg/L, whereas the inhibition of algae yield resulted in a EyC50 (72 h) of 18.37 mg/L. Therefore, the test item is acutely harmful to aquatic algae.
Microorganisms
Sewage sludge microorganisms were exposed to the test item (CIBA-GEIGY, 1989). The IC50 value based on respiration rate was ≥100 mg/L after a 3 h contact time. Therefore, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
In general, it should be mentioned that the composition contains < 1 % p-Nonylphenol (CAS 104-40-5) as impurity. p-Nonylphenol is part of the dossier "4-Nonylphenol, branched and linear [substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof]" for the Candidate List of Substances of Very High Concern for Authorisation (Decision number ED/169/2012; Equivalent level of concern having probable serious effects to the environment (Article 57 f)).
However, no decision is made by now.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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