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EC number: 288-917-4 | CAS number: 85940-28-9
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Introduction
No determination was possible according to Method A8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Methods 107 and/or 117 of the OECD Guidelines for Testing of Chemicals, due to the following reasons:
An assessment of the emulsification properties of the test item was carried out with the test item prepared in water saturated n-octanol and shaken with an equal amount of n-octanol saturated water. Observations after this test showed that the two immiscible phases emulsified easily; additionally, after 1 hour standing, there were still three layers visible, the middle layer being a white emulsion. It was therefore considered that as the test item also gave a positive surface-active result in the Surface Tension test (See Section 7), the test item can be considered to be surface-active. Surface-active items are not suitable for determination by the flask-shake method or the HPLC method.
Estimation using the ratio of the solubility of the test item in n-octanol and water would also be unreliable due to the possible self-aggregation properties shown by surface-active substances.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 8.87
- at the temperature of:
- 20 °C
Additional information
- An assessment of the emulsification properties of the test item was carried out with the test item prepared in water saturated n-octanol and shaken with an equal amount of n-octanol saturated water. Observations after this test showed that the two immiscible phases emulsified easily; additionally, after 1 hour standing, there were still three layers visible, the middle layer being a white emulsion. It was therefore considered that as the test item also gave a positive surface-active result in the Surface Tension test (See Section 7.6 Surface Tension Harlan Laboratories study number 41003463), the test item can be considered to be surface-active. Surface-active items are not suitable for determination by the flask-shake method or the HPLC method.
- Estimation using the ratio of the solubility of the test item in n-octanol and water would also be unreliable due to the possible self-aggregation properties shown by surface-active substances.
Introduction
No determination was possible according to Method A8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Methods 107 and/or 117 of the OECD Guidelines for Testing of Chemicals, due to the following reasons:
Method
Therefore, the partition coefficient was estimated using the computer-based specialist estimation software, KOWWIN, version 1.67a (Sept 2008), © 2000 U.S. Environmental Protection Agency.
The substance was modelled without the zinc atom as the per EPIsuite recommendations.
Conclusion
Using a computer-based atom fragment contribution method, KOWWIN, version 1.67a, © 2000 US Environmental Protection Agency, the partition coefficient (log10 Pow) has been estimated 8.87.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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