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EC number: 600-736-8 | CAS number: 106276-80-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 105, flask method
- Principles of method if other than guideline:
- The partition coefficient was estimated based on the ratio of the solubilities in n-octanol and in water.
The individual solubilities were determined by the flask method based on OECD Guideline 105 and the ETAD method. The quantification was analyzed by HPLC-UV. - GLP compliance:
- no
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 0
- Temp.:
- 23 °C
- Remarks on result:
- other: no data on pH
- Details on results:
- The concentration of the pigment in water and in n-octanol was determined by HPLC-UV measurements:
Solubility in water: <30 µg/L
Solubility in n-octanol: <30 µg/L
No test item could be detected with a detection limit of 30 μg/L inboth solvents. - Conclusions:
- The partition coefficient of test substance was estimated to be log Pow= 0 at 23°C.
Reference
Estimation of log Pow:
Pow= c(n-octanol) / c( water)= 30.0 µg/L / 30.0 µg/L= 1
Log Pow= 0
Description of key information
Estimated based on solubility ratio:
log Pow= 0 at 23°C
Key value for chemical safety assessment
Additional information
Bulk form:
The partition coefficient was estimated based on the ratio of the solubilities in n-octanol and in water.
The individual solubilities were determined by the flask method based on OECD Guideline 105 and the ETAD method. The quantification was analyzed by HPLC-UV.
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