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The toxicity of 4-Nitrophenol to soil macroorganisms has been extensively reviewed by international groups of experts, i.e. BUA report No.75 (1992) and IPCS CICAD (2000). In the tests conducted according to the OECD Guideline 207, the adverse effects of 4 -Nitrophenol on earthworms were examined in several independent studies. In the contact test, in which animals are exposed on filter paper soaked with the test substance, a 48 -h LC50 value of 0.7 -2.7 g/cmE2 was established, with Eisenia fetida and Eudrilus eugeniae being the most sensitive species tested (Roberts & Dorough 1984, Neuhauser et al. 1985, 1986; cited from the IPCS CICAD 2000). When exposed in an artificial soil mixture, 14 -day LC50 values were in the range of 38 -67 mg/kg soil, again with Eisenia fetida and Eudrilus eugeniae as most sensitive species tested (Ballhorn et al. 1984, Marquart et al. 1984, Neuhauser et al. 1985, 1986; cited from the IPCS CICAD 2000).