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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Measured data: EC50, 96hr: monoethylene glycol 6500-13000mg/l
TGK (~EC5), 8 day: diethylene glycol: 2700, triethylene glycol: >10000mg/l
QSAR values: 96hr EC50: 3500, 9400, 20500mg/l respectively
QSAR Chv values: 480, 1200, 2500mg/l respectively

Key value for chemical safety assessment

EC50 for freshwater algae:
6 500 mg/L

Additional information

Test data is available for all constituents of this substance. However, two of the studies used 8 day testing protocols that are now regarded as unreliable (growth in exponential state cannot be maintained over such a period.) QSAR data suggests that toxicity decreases with increasing molecular weight of the ethylene glycol series and therefore predicts that monoethylene glycol (MEG) will be the most toxic. The lowest end of the range of the 96hr EC50 values for MEG is therefore used as a conservative value for the EC50 of the substance. No reliable EC10 figure can be derived. There is no data on saltwater species.