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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: early study report, short study description

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1968
Report date:
1968

Materials and methods

Principles of method if other than guideline:
according to BASF-internal standards
GLP compliance:
no
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
30% solution in aqua dest.

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water
Details on oral exposure:
Recording of symptoms for 7 days after application resp. 14 days
Doses:
3200, 6400, 8000, 10000 cmm/kg
No. of animals per sex per dose:
20
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
7 712 mg/kg bw
Based on:
test mat.
Mortality:
Dead animals after 7 days observation period:
19/20 in 10000 cmm/kg dose group
16/20 in 8000 cmm/kg dose group
5/20 in 6400 cmm/kg dose group
0/20 in 3200 cmm/kg dose group
Clinical signs:
depression, narcosis
Gross pathology:
Animals that died: kidney damage

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU