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EC number: 202-653-9 | CAS number: 98-29-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- report date: 2010-01-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Key result
- Boiling pt.:
- 290.5 °C
- Atm. press.:
- 1 013 hPa
- Conclusions:
- The boiling point of 4-TBC is 290.5°C +/- 0.1°C.
- Executive summary:
In a study (Processium, 2010), the boiling point of 4-tert-butylpyrocatechol was assessed using the differential scanning calorimetry, according to the regulation (EC) n°440/2008, A.2, and to the OECD Guideline n°103.
A test item amount of 5 mg was heated up from 30 to 300°C with a rate of 10°C/min. During the experiment, two samples were measured. The quantities of heat absorbed or released were measured by Differential Scanning Calorimetry and recorded. A reference sample (around 5 mg) of benzoic acid was measured in order to evaluate the experimental procedure.
The results of the boiling point of 4 -TBC were: 289.8°C and 291.2°C and of the reference item: 249.7°C.
According to the results of the reference item, the test has to be considered as valid.
In conclusion, the boiling point of 4 -tert-butylpyrocatechol is 290.5°C +/- 1.0°C.
This study is classified as acceptable and satisfies the guideline requirements for a boiling point study.
Reference
Atmospheric pressure during the assay has not been measured; the boiling temperature was given without any correction.
Result of the boiling point:
|
Test item |
Reference item |
|||
|
Assay 1 |
Assay 2 |
Mean(+/- Standard deviation) |
Measure |
range |
Weight (mg) |
5.39 |
5.45 |
- |
5.09 |
- |
Boiling point (°C) |
289.8 |
291.2 |
290.5 +/- 1.0 |
249.7 |
249.0 - 250.5 |
According to the results of the reference item, the test has to be considered as valid.
Description of key information
Boiling point: 290.5°C +/- 0.1°C
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 290.5 °C
Additional information
One experimental study (Processium, 2010) with reliability 1 according to Klimisch was available and was selected as key study. Boiling point was determined according to the regulation (EC) n°440/2008, A.2.
Data coming from peer-review handbooks were available. As the values are in the same range, they are used in a supporting approach.
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