Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-180-8 | CAS number: 92-70-6
Endpoint summary
Administrative data
Description of key information
A secondary source describes data on irriation to skin and eyes of rabbits (Anonymous 2004). Whereas the information on skin irritation indicates transient mild effects, effects on eyes are considered severe. Irritation of the respiratory tract is assumed from the low pKa and the effects on eye.
Key value for chemical safety assessment
Additional information
The reported data was described as OECD guideline compliant in the OECD SIDS dossier (Anonymous 2004)
Findings for eyes were described as conjunctivitis and diffuse corneal opacities at 24, 48 and 72h. One animal showed iritis at 24 and 48h. After 7 days, corneal vascularization was observed in all animals. Regarding skin irritation, mild findings were observed for edema and erythema which were reversible within 48h.
Considering the low pKa and the effects observed for eyes, the BONA is expected to cause respiratory irritation.
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
The available study are considered reliable and suitable for classification purposes under 67/548/EEC. As a result the substance is considered to be classified as a severe irritant to eyes and as irritating to the respiratory system under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC.
Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008. As a result the substance is considered to be classified as a severe irritant to eye and as irritating to the respiratory system under Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
