Registration Dossier
Registration Dossier
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EC number: 240-934-8 | CAS number: 16893-85-9
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute toxicity of fluoride compound
- Author:
- Simons P., Pierron A.
- Year:
- 1 937
- Bibliographic source:
- Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Acute dermal toxicity in frogs
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Disodium hexafluorosilicate
- EC Number:
- 240-934-8
- EC Name:
- Disodium hexafluorosilicate
- Cas Number:
- 16893-85-9
- Molecular formula:
- F6Si.2Na
- IUPAC Name:
- disodium hexafluorosilicate
Constituent 1
Test animals
- Species:
- other: Frogs
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- other: Frogs were introduced in solutions of disodium hexafluorosilicate
- Vehicle:
- water
- Details on dermal exposure:
- No data
- Duration of exposure:
- No data
- Doses:
- No data
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LDLo
- Effect level:
- ca. 448 mg/kg bw
Applicant's summary and conclusion
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