Registration Dossier
Registration Dossier
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EC number: 240-934-8 | CAS number: 16893-85-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Results on skin irritation obtained from literature indicate that damage caused on intact skin after application of 4h of tdisodium hexafluorosilicate under occlusion provide reversible irritating effects. If applied for 23h, reversibility is also observed. Reversibility of the lesions was complete by day 7. Irritating effects were measured based on PCI values. For disodium hexafluorosilicate, PCI= 0.04, which corresponds to non irritating. The value of the pH given by the substance seemed not to have any effects on PCI.
Experimental in vitro eye irritation study demonstrated that disodium hexafluorosilicate is not eye irritating.
Justification for classification or non-classification
No classification is proposed since experimental results and data on reliable publications indicate the absence of irritating properties.
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