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EC number: 202-785-7 | CAS number: 99-76-3
Testing for sensitising properties of Methylparaben was performed in male and female guinea pigs according to the Maurer Optimization Test. Intradermal induction was performed using 0.1 % Methylparaben (10 injections). The first challenge was carried out with 0.1% Methylparaben (intradermal) 14 days after the last induction application and the second challenge was conducted with 5% Methylparaben (epidermal) in soft white petrolatum after further 10 days rest.
Methylparaben induced allergic reactions in a few animals, but according to the standard evaluation, not significant and therefore the test substance is not considered to have sensitising properties.
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