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EC number: 266-039-2 | CAS number: 65997-03-7 The low boiling fraction obtained by the distillation of tall oil. Contains fatty acids such as palmitic, stearic, oleic and linoleic as well as neutral materials.
Crude Tall Oil (0.1 ml) was instilled into the conjunctival sac of the right eye of each of three New Zealand white rabbits. The eyes were held closed for one second to prevent loss of the test substance. The untreated left eyes served as the controls. Both eyes were examined within 24 hours before the instillation, and approximately 1, 24, 48 and 72 hours post-instillation. There were no deaths or signs of toxicity in any of the animals. The untreated eyes were normal at each observation. One hour post-instillation all animals had grade 1 conjunctival redness, and 2/3 animals had grade 1 conjunctival chemosis. Ocular discharge was noted in all animals one hour after instillation. There were no signs of irritation at any other time point. There were no effects on the cornea and iris. Crude Tall Oil was concluded not to be irritating to the eyes.
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