Registration Dossier
Registration Dossier
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EC number: 931-434-7 | CAS number: -
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR Database
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July 2008
- Principles of method if other than guideline:
- Dermwin v2.01 (Q)SAR database report
Test material
- Reference substance name:
- Esterification products of D-glucitol with C8 – C16 (even-numbered) and C18 unsaturated fatty acids
- EC Number:
- 931-434-7
- Cas Number:
- 1338-39-2
- Molecular formula:
- C18H34O6
- IUPAC Name:
- Esterification products of D-glucitol with C8 – C16 (even-numbered) and C18 unsaturated fatty acids
Constituent 1
Results and discussion
- Absorption in different matrices:
- Dermal absorption of the test substance was predicted to be very low with an estimated dermal permeability coefficient (Kp) of 0.00222 cm/h and a dermal absorption rate of 0.00076 mg/cm²/h (=0.000189 mg/cm²/event).
Applicant's summary and conclusion
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