Resin acids and Rosin acids, fumarated, esters with pentaerythritol

PBT assessment

PBT assessment: overall result

PBT status:

the substance is not PBT / vPvB

Justification:

The rosin adduct ester category consists of fumarated and maleated esters of glycerol and pentaerythritol. The substances consist of ester constituents (mono-, di- and tri- glycerol esters and mono-, di-, tri- and tetra- pentaerythritol esters), and free resin acids.. The PBT assessment of rosin adduct ester substances therefore considers the PBT potential of each of the constituents, rather than the substance as a whole. The constituents of each substance within Category 4 are expected to be similar and thereforea single PBT assessment covering all of the constituents in this category is justified.

Guidance for mono-constituents is available from ECHA; however, for complex substances such as Unknown or Variable Composition, Complex reaction products or Biological materials (UVCBs) there is currently little guidance on how the PBT/vPvB assessment should be conducted. A pragmatic approach for UVCBs is to evaluate all the individual constituents present in the substance at a concentration of≥0.1% for their PBT properties.

The previous PBT assessments submitted for this Category have been updated. As part of this update, all of the blocks of constituents listed in the Substance Identity Profile for substances in this category have been included and at least 1 representative structure has been identified for each block. The previous QSARs have also been re-run to ensure they are up to date and valid. Detailed analysis of each individual constituent within the category is not available and so a list of constituents thought to be present has been developed from information in the Substance Identity Profiles for each substance. All identified constituents were assessed individually for their PBT properties.

There is little data available on the individual constituents found in substances in this category. As such a block approach has been applied using data from the Substance Identity Profile. Constituents that are thought to be present in each block were identified and used to assess if the blocks are potentially PBT/vPvB.The rosin adduct ester category consists of fumarated and maleated esters of glycerol and pentaerythritol. The substances consist of ester constituents (mono-, di- and tri- glycerol esters and mono-, di-, tri- and tetra- pentaerythritol esters), and free resin acids. Therefore, non-reacted rosin acids, fatty acids and neutrals remain as constituents in the UVCB. Representative constituents have been assigned to the latter two blocks based on the H4R consortium’s knowledge of the composition of the parent Rosin, and Resin Acids and Rosin Acids and their salts.

 The blocks and their representative constituents that were assessed are listed in Table1.

Table 1 Blocks present in this category and representative structures for each block.

Block	Constituent
Total Esters (Rosin acids + Poly esters)	Rosin adduct, mono-Glycerol
	Rosin adduct, di- Glycerol
	Rosin adduct, tri- Glycerol
	Rosin adduct, mono-Pentaerythritol
	Rosin adduct, di- Pentaerythritol
	Rosin adduct, tri- Pentaerythritol
	Rosin adduct, tetra- Pentaerythritol
	Rosin adduct, tri- Glycerol
	Rosin adduct, tri- Pentaerythritol
	Rosin adduct, di-(di) Glycerol
	Rosin adduct, tetra-(tri) Glycerol
Fumaropimaric acid	Fumaropimaric acid
Maleopimaric acid	Maleopimaric acid/anhydride
Non-reacted rosin acids	Abietic acid
	Neoabietic acid
	Palustric acid
	Levopimaric acid
	Dehydroabietic acid
	Hydroabietic acid
	Pimaric acid
	7,15-pimaradienoic acid
	Delta Pimaric acid
	Isopimaric acid
	Sandaracopiramic acid
	Delta Isopimaric acid
	Communic acid
	Anticopatic acid
	Lambertiaric acid
	Mercusic acid
	Acetylisocupressic acid
	Acetylimbricataloic acid
	Imbricataloic acid
Fatty acids	16:0 fatty acid
	16:1 fatty acid
	18:1 fatty acid (9)
	18:2 fatty acid (9,12)
	18:3 fatty acid (5,9,12)
	20:3 fatty acid (5,11,14 + 7,11,14)
Neutral fraction	Abietadiene
	Pimaradiene
	Isopimaradiene
	Palustradiene
	Dehydroabietadiene
	Abietal
	Pimaral
	Isopimaral
	Palustral
	Dehydroabietal

Following the Screening assessment detailed above the data gathered suggests that whilst conclusions on Persistence cannot be drawn for the constituents where data are from QSARs alone, none of the constituents are expected to be Bioaccumulative (Table 9). It is noted that, even if the data on bioaccumulation is exclusively from QSARs for this substance, the models used are reliable, well documented and well known and fit these types of constituents, even those substances that have a higher Kow than the training data set. The Predicted BCF values in both models were much lower than the 2000 L/kg criterion for B in the Regulation and therefore there is high confidence that there are no constituents of concern in this substance.