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PBT assessment

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PBT assessment: overall result

Reference
Name:
3-(2,3-epoxypropoxy)propyltrimethoxysilane
Type of composition:
boundary composition of the substance
State / form:
liquid
Reference substance:
Composition 1
PBT status:
the substance is not PBT / vPvB
Justification:

The assessed substance, [3-(2,3-epoxypropoxy)propyl]silanetriol is the hydrolysis product of the submission substance.

3-(2,3-epoxypropoxy)propyltrimethoxysilane hydrolyses rapidly in contact with water to form [3-(2,3-epoxypropoxy)propyl]silanetriol and methanol.

 

The silanol hydrolysis product, [3-(2,3-epoxypropoxy)propyl]silanetriol may persist in the environment but does not meet the criteria for B or T, and therefore the hydrolysis product should not be concluded as PBT or vPvB.

There is a testing proposal to clarify the genetic toxicity potential for germ cells following a positive result in a comet assay.