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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Experimental data on the chronic toxicity of pentacalcium hydroxide tris(orthophosphate are not available. Read across data indicate that the substance is not acutely toxic to fish. Bioaccumulation of Tricalcium bis(orthophosphate) is not anticipated. When dissolved in water (and so animal tissues/fluids) it will dissociate to the ions "phosphate" and "calcium”. Both ions are ubiquitous in the environment and are essential micronutrients for many organisms. Calcium and phosphate are natural ionic components of blood, cell fluids, etc.. Calcium phosphate, in the form of hydroxyapatite, is an essential part of vertebrate bones. Phosphate is also needed for the synthesis of phospholipids, a major component of cell membranes. Thus, the uptake and concentration level of phosphate and calcium is strongly controlled and regulated by a number of mechanisms, whereby the metabolism of calcium and phosphate is interrelated. Excess calcium and phosphate is excreted. Long-term toxicity is thus considered unlikely.

A chronic toxicity of the substance is not anticipated due to the lack of acute toxicity and the fact that calcium and phosphate are essential micronutrients for fish.