Octan-1-ol

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009-09-10

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods with acceptable restrictions

Remarks:

Test procedure in accordance with national standard methods (ASTM) without GLP. Measured by 100 °F (ca. 38°C) instead of 20°C.

Qualifier:

according to guideline

Guideline:

other: ASTM D 2879

Deviations:

no

GLP compliance:

no

Type of method:

isoteniscope

Key result

Test no.:

#1

Temp.:

ca. 38 °C

Vapour pressure:

ca. 0.764 mBar

Remarks on result:

other: measured temperature: 100 °F

Measurement

Vapor Pressure at 100°F (Calculated): 0.5734 mm Hg

Conclusions:

A vapour pressure value of 0.7645 mBar (76.5 Pa) at 38°C was determined for the substance using a relevant test method. The result is considered to be reliable.

Executive summary:

Octan-1-ol was determined according ASTM D2879. The vapour pressure was determined to be 0.76 mbar at 38°C.

Reference 2

Endpoint:

vapour pressure

Type of information:

other: Data obtained from a secondary source

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Temp.:

60.1 °C

Vapour pressure:

2.2 hPa

Conclusions:

A vapour pressure of 2.2 hPa at 60.1°C was reported for the substance in a secondary source to which reliability could not be assigned.

Reference 3

Endpoint:

vapour pressure

Type of information:

other: Data obtained from a collection of reliable data

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

The value is the extrapolated value at ambient temperature based on peer-reviewed raw vapour pressure data across a broad range of temperatures. The reference source is a well-known and reliable source of critically-reviewed vapour pressure data, which cites the original source of the data.

Principles of method if other than guideline:

No details are available on the guideline used to determine this result.

GLP compliance:

no

Temp.:

25 °C

Vapour pressure:

9.95 Pa

Temp.:

25 °C

Vapour pressure:

10.1 Pa

Transition / decomposition:

no

The value at 25ºC is determined using the Antoine Equation by applying three standard coefficients for use in that equation, derived

by Boublik et al. from reliable raw data.

Conclusions:

Vapour pressure values of 9.95 and 10.1 Pa at 25ºC were reported in a collection of reliable data which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable.

Reference 4

Endpoint:

vapour pressure

Type of information:

other: Data obtained from a handbook

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

No details are available on the guideline used to determine this result.

GLP compliance:

not specified

Temp.:

25 °C

Vapour pressure:

0.1 hPa

Conclusions:

A vapour pressure value of 0.10 hPa at 25ºC was reported in a collection of reliable data which has been subject to peer-review. The result is considered to be reliable.

Description of key information

The vapour pressure of a commercial octan-1-ol product is 0.7645 mBar (76.45 Pa) at 38°C. It is supported by a value of 10.1 Pa at 25°C, taken from a reliable reference source (Boublik et al., 1984). A consistent and reliable measurement of 10 Pa at 25°C using a highly pure sample is available (Daubert and Danner, 1989). These values are also supported by a predicted vapour pressure value of 11 Pa at 25°C using a validated QSAR estimation method. The quantified value at ambient temperature from Daubert and Danner is used in the chemical safety assesment.

Key value for chemical safety assessment

Vapour pressure:

10 Pa

at the temperature of:

25 °C

Additional information

A vapour pressure value of 0.7645 mBar (76.5 Pa) at 38°C was determined for octan-1-ol with the use of an isoteniscope method in accordance with ASTM D 2879. The result is considered to be reliable.

It is supported by a value of 10.1 Pa at 25°C, taken from a reliable reference source (Boublik et al., 1984). A consistent and reliable measurement of 10 Pa at 25°C using a highly pure sample is available (Daubert and Danner, 1989). These values are also supported by a predicted vapour pressure value of 11 Pa at 25°C using a validated QSAR estimation method.

In available secondary sources to which reliability could not be assigned, vapour pressure values of 0.031 hPa at 20°C, 1.3 hPa at 54°C and 2.2 hPa at 60.1°C were reported for the substance.

The quantified value at ambient temperature from Daubert and Danner is used in the chemical safety assesment.

Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:

As chain length increases, vapour pressure decreases. This is because molecular weight is higher and intermolecular forces in the substance are all higher.