Registration Dossier
Registration Dossier
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EC number: 203-080-7 | CAS number: 103-11-7
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only abstract available
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicology of ethylhexyl acrylate.
- Author:
- Tedder YR et al.
- Year:
- 1 967
- Bibliographic source:
- Mater. Nauch-Prakt. Konf. Molodykh, Gig. Sanit. Vrachei, 11th: 226, (Chemical Abstracts 72, 29913x)
Materials and methods
- Principles of method if other than guideline:
- General toxicity was examined on white rats receiving i.p. doses of ethylhexyl acrylate.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-ethylhexyl acrylate
- EC Number:
- 203-080-7
- EC Name:
- 2-ethylhexyl acrylate
- Cas Number:
- 103-11-7
- Molecular formula:
- C11H20O2
- IUPAC Name:
- 2-ethylhexyl acrylate
- Test material form:
- liquid
- Details on test material:
- - Test substance: 2-ethylhexyl acrylate
- Chemical name: 2-propenoic acid, 2-ethylhexyl ester
- Analytical Purity: 99.5% stabilized with 20 ppm of p-methoxyphenol
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
- Mortality:
- Some mortality occurred.
- Clinical signs:
- no data
- Body weight:
- no data
- Gross pathology:
- In some animals that died during the experiments, dystrophic changes in the epithelium of distal sections of the nephrons were observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
