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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010-06-15 to 2010-07-01
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Principles of method if other than guideline:
not reported
GLP compliance:
no
Type of method:
column elution method
Water solubility:
< 0.05 mg/L
Temp.:
20 °C
pH:
ca. 6.2

Flow rate (mL/h)

Fraction no.

Water solubility (mg/L)

pH-value

25

1

< 0.05

6.2

 

2

< 0.05

6.1

 

3

< 0.05

6.0

 

4

< 0.05

6.2

 

5

< 0.05

6.1

 

6

< 0.05

6.1

 

7

< 0.05

6.2

12

1

< 0.05

6.4

 

2

< 0.05

6.3

 

3

< 0.05

6.3

 

4

< 0.05

6.2

 

5

< 0.05

6.1

 

6

< 0.05

6.2

 

7

< 0.05

6.3

Endpoint:
water solubility
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
Please refer to the available category justification
Reason / purpose for cross-reference:
read-across source
Water solubility:
< 0.05 mg/L
Temp.:
20 °C
pH:
ca. 6.2
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well documented study report which meets basic scientific principles
Principles of method if other than guideline:
not reported
GLP compliance:
no
Type of method:
other: not reported
Water solubility:
< 0.05 g/L
Temp.:
25 °C
Remarks on result:
other: Value from company report, no data available for pH.

Description of key information

The water solubility is < 0.05 mg/L at 20 °C.

Key value for chemical safety assessment

Additional information

The key value of water solubility of the substance is estimated by using category approach, i.e. read-across from its main constituent C16 palmitic acid (CAS 57-10-3). Because water solubility of fatty acid decreases with the chain length, the C16 palmitic acid has the highest water solubility within this composition. It is supported by data for the substance itself, but with less precision (< 50 mg/L).