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Toxicological information

Genetic toxicity: in vivo

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Administrative data

genetic toxicity in vivo
Type of genotoxicity: other: several in-vivo genotoxicity studies
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Comparable to guideline study with limitations which do not impair the overall conclusion from the data. Sufficiently detailed description of the test procedure in accordance with scientific standards (critical supporting information given, such as species tested, substance identity and dosing procedure).

Data source

Materials and methods

Type of assay:
other: summary of data reported

Results and discussion

Applicant's summary and conclusion

Executive summary:

Further discussed in 13 Assessment Reports - analogy to titania and alumina