Registration Dossier
Registration Dossier
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EC number: 411-540-5 | CAS number: 130201-57-9 REACTIVE RED SR 6947; ROUGE REACTIF SR 6947
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20.06.1991 to 20.06.1991
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EU Method A.7
- Deviations:
- no
- Principles of method if other than guideline:
- The content of Monoazo Red SR 6947 in fat simulant at the maximum solubility is determined by spectrophotometry after extraction with water.
- GLP compliance:
- yes
- Remarks:
- Swiss GLP
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: SR 6947 - Medium:
- standard fat
- Remarks:
- fat simulant HB 307, batch 27
- Solubility:
- <= 0.05 mg/100 g solvent
- Temp.:
- 37 °C
- Test substance stable:
- yes
- Conclusions:
- The fat solubility of FAT 40406/A is lower than 0.05 mg/100 g fat at 37°C.
- Executive summary:
In a GLP compliant study, performed according to EU method A.7, the fat solubility of the test substance was determined.
The content of the test substance in fat simulant HB 307 was determined by spectrophotometry after extraction with water. The average fat solubility was determined from eight experiments was found to be lower than 0.05 mg/100 g fat at 37°C.
Reference
Description of key information
The fat solubility of Reactive Red 245 is lower than 0.05 mg/100 g fat at 37°C.
Key value for chemical safety assessment
- Solubility in mg/100g standard fat:
- 0.05
- At the temperature of:
- 37 °C
Additional information
In a GLP compliant study, performed according to EU method A.7, the fat solubility of the test substance was determined.
The content of the test substance in fat simulant HB 307 was determined by spectrophotometry after extraction with water. The average fat solubility was determined from eight experiments was found to be lower than 0.05 mg/100 g fat at 37°C.
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