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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17.06.1991 to 21.06.1991
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Remarks:
Swiss GLP
Type of method:
flask method
Specific details on test material used for the study:
Name: FAT 40406/A
Purity: 89.3%
Water solubility:
339 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
7.3
Details on results:
The substance forms a viscose paste at a concentration of 1000 g/L. Therefore it is not possible to use a five fold saturation concentration for the determination of the solubility, as required by the EEC method. Consequently the solubility can be higher than this mean value.

Flask

1

2

3

Weight of the test substance (g)

Volume of water (ml)

Temperature during agitation (deg C)

Agitation duration (hrs)

Temperature of equilibration (deg C)

Equilibration duration (hrs)

pH of the solution at 20 deg C

(after centrifugation)

2.0576

5.0

30

24

20.0

24

7.3

2.0576

5.0

30

24

20.0

24

7.3

2.0611

5.0

30

72

20.0

24

7.3

Water solubility (g/l)

332.8

341.7

342.7

Mean value (g/l)

339

Conclusions:
The water solubility of the FAT 40406/A was found to be 339 g/L at 20°C.
Executive summary:

A GLP compliant study was performed on FAT 40406/A according to EU Method A.6 and OECD test guideline 105, as per flask method to assess the water solubility of the test substance.

Based on the findings of the study, the water solubility was found to be 339 g/L at 20°C.

Description of key information

The water solubility of Reactive Red 245 is 339 g/L at 20°C. 

Key value for chemical safety assessment

Water solubility:
339 g/L
at the temperature of:
20 °C

Additional information

A GLP compliant study was performed on FAT 40406/A according to EU Method A.6 and OECD test guideline 105, as per flask method to assess the water solubility of the test substance.

Based on the findings of the study, the water solubility was found to be 339 g/L at 20°C

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