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EC number: 927-241-2 | CAS number: -
Repeated Dose Oral 90d – NOAEL >=5000 mg/kg for rats (similar to OECD TG 408)Repeated Dose Inhalation 90d – NOAEL >= 10400 mg/m3 for rats (similar to OECD TG 413)
Oral: C9-C14 aliphatic, < 2% aromatic hydrocarbon fluids are expected to have a low order of repeated dose toxicity by the oral route of exposure. All tests were performed in a manner similar or equivalent to currently established OECD guidelines. In a repeated dose study where C9-C14 aliphatic, < 2% aromatic hydrocarbon fluids were administered via oral gavage, no signs of toxicity were observed at the maximum experimental dose tested, 5000 mg/kg/day.
Inhalation: In a repeated dose study where C9-C14 aliphatic, < 2% aromatic hydrocarbon fluids were administered via inhalation, no signs of toxicity were observed at 10400 mg/m3. Based on these observations, the repeat inhalation concentration NOAEL is >=10400 mg/m3 (10.4 mg/L) for C9-C14 aliphatic, < 2% aromatic hydrocarbon fluids.
These findings do not warrant the classification of C9-C14 aliphatic, < 2% aromatic hydrocarbons as a repeated dose toxicant under the new Regulation (EC) 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP) or under the Directive 67/548/EEC for dangerous substances and Directive 1999/45/EC for preparations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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