Registration Dossier
Registration Dossier
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EC number: 269-665-4 | CAS number: 68308-74-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21-day NOEL was found to be 0.75 mg/L and the 21-day LOEL for both reproduction and immobilization was determined to be >0.75 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.75 mg/L
Additional information
A 21 -dayDaphnia magnareproduction test was conducted according to OECD guideline 211 and EC Method C.20. Due to the low aqueous solubility and complex nature of the test item, for the purposes of the test, the test item was prepared as a Water Accommodated Fraction (WAF). Nominal loading rates of 0.0072, 0.023, 0.072, 0.23 and 0.75 mg/L loading rate WAF. Test solutions were renewed daily.
The flasks were maintained at 20°C to 22 °C with a photoperiod of 16 hours light (722 to 782 lux) and 8 hours darkness. On a daily basis the numbers of live and dead of the "Parental" (P1) generation, the numbers of live and dead "Filial" (F1) Daphnia and the number of discarded unhatched eggs were counted. The number of Daphnia with eggs or young in the brood pouch was determined daily.
The 21-day NOEL was found to be 0.75 mg/L, and the 21-day LOEL for immobilization and reproduction was determined to be >0.75 mg/L.
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