Registration Dossier
Registration Dossier
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EC number: 200-338-0 | CAS number: 57-55-6
Endpoint summary
Administrative data
Description of key information
Additional information
There are several guideline studies available for freshwater fish. The studies are all static and the test concentrations are measured in most of the studies. The lowest observed effect concentration is a 96 -h LC50 value of 40613 mg/l in a study with Oncorhynchus mykiss (Beak Consultants Limited, 1995).
The effect concentration determined in marine fish is a 96 -h LC50 of >10,000 mg/l in Scophthalmus maximus (Halliburton Energy Services, 2004). An EC50 value could not be determined, therefore this study will not be used in the assessment.There are several guideline studies available for freshwater invertebrates. For freshwater invertebrates the lowest observed effect concentration is a 48-h LC50 value of 18340 mg/l in Ceriodaphnia dubia (Pillard, 1995). In marine water, the lowest 96-h LC50 is 18800 mg/l in Mysidopsis bahia (new name: Americamysis bahia) (ARCO Chemical Company, 1990). Both values will be used in the assessment.
One chronic guideline test is available with the freshwater invertebrate Ceriodaphnia. The 7-d NOEC is 13020 mg/l (measured concentration) (Pillard, 1995).
This value will be used in the assessment.
Experimental data are available with fresh water and marine algae. In fresh water, the 96-h EC50 is 19000 mg/l in Pseudokirchnerella subcapitata (reported as Selenastrum capricornutum) (ARCO Chemical Company, 1990f). In marine water, the 96-h EC50 is 19100 mg/l in Skeletonema costatum (ARCO Chemical company, 1990g). These values will be used in the assessment.
Reliable test data are available for toxicity to microorganisms. In a near guideline test with Pseudomonas putida an 18-h NOEC of >20,000 mg/l was determined in a growth inhibition test. Nominal values were reported (The Dow Chemical Company, 1992). This value will be used in the assessment.
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