Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: long-term
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable study, peer reviewed, no analytical dose verification.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Dietary cobalt supplements and the growth and reproduction of the earthworm Eisenia foetida
Author:
Neuhauser EF et al.
Year:
1984
Bibliographic source:
Soil Biology and Biochemistry 16: 521–523
Reference Type:
secondary source
Title:
CICAD 69, Cobalt and inorganic cobalt compounds
Author:
WHO
Year:
2006

Materials and methods

Principles of method if other than guideline:
Reproduction and growth test, 24 weeks
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
Cobalt dichloride, hexahydrate
IUPAC Name:
Cobalt dichloride, hexahydrate
Constituent 2
Reference substance name:
7791-13-1
EC Number:
616-574-6
Cas Number:
7791-13-1
IUPAC Name:
7791-13-1
Details on test material:
- Analytical purity: no data

Sampling and analysis

Analytical monitoring:
no

Test substrate

Vehicle:
no

Test organisms

Test organisms (species):
Eisenia fetida
Animal group:
annelids

Study design

Study type:
laboratory study
Substrate type:
natural soil
Limit test:
no
Total exposure duration:
24 wk

Test conditions

Nominal and measured concentrations:
9.4, 17.6, 25.9, 91.9 µg Co g-1 d.w. in horse manure
Reference substance (positive control):
no

Results and discussion

Any other information on results incl. tables

The authors observed significantly increased maximum weights compared to the control worms which were exposed to 9.4 µg Co g-1. The highest Co addition (82.5 µg Co g-1, total 91.9 µg Co g-1) caused no increase in maximum weight over controls, but resulted in a statistically significant lag in early growth compared to that of all other groups. Significantly more cocoons were produced by worms fed 17.6 or 25.9 µg Co g-1 compared with those fed 9.4 or 91.9 µg Co g-1.

Applicant's summary and conclusion