Cobalt di(acetate)

Toxicity to soil macroorganisms except arthropods

Administrative data

Endpoint:

toxicity to soil macroorganisms except arthropods: long-term

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Acceptable study, peer reviewed, no analytical dose verification.

Data source

Reference

Reference 1

Reference Type:

publication

Title:

Dietary cobalt supplements and the growth and reproduction of the earthworm Eisenia foetida

Author:

Neuhauser EF et al.

Year:

1984

Bibliographic source:

Soil Biology and Biochemistry 16: 521–523

Reference 2

Reference Type:

secondary source

Title:

CICAD 69, Cobalt and inorganic cobalt compounds

Author:

WHO

Year:

2006

Materials and methods

Principles of method if other than guideline:

Reproduction and growth test, 24 weeks

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Cobalt dichloride, hexahydrate

IUPAC Name:

Cobalt dichloride, hexahydrate

Constituent 2

Reference substance name:

7791-13-1

EC Number:

616-574-6

Cas Number:

7791-13-1

IUPAC Name:

7791-13-1

Details on test material:

- Analytical purity: no data

Sampling and analysis

Analytical monitoring:

no

Test substrate

Vehicle:

no

Test organisms

Test organisms (species):

Eisenia fetida

Animal group:

annelids

Study design

Study type:

laboratory study

Substrate type:

natural soil

Limit test:

no

Total exposure duration:

24 wk

Test conditions

Nominal and measured concentrations:

9.4, 17.6, 25.9, 91.9 µg Co g-1 d.w. in horse manure

Reference substance (positive control):

no

Results and discussion

Any other information on results incl. tables

The authors observed significantly increased maximum weights compared to the control worms which were exposed to 9.4 µg Co g-1. The highest Co addition (82.5 µg Co g-1, total 91.9 µg Co g-1) caused no increase in maximum weight over controls, but resulted in a statistically significant lag in early growth compared to that of all other groups. Significantly more cocoons were produced by worms fed 17.6 or 25.9 µg Co g-1 compared with those fed 9.4 or 91.9 µg Co g-1.