Registration Dossier
Registration Dossier
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EC number: 611-005-8 | CAS number: 53513-80-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline-Studie, ausführlich dokumentiert
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- D-Penicillamin-Bleisalz
- IUPAC Name:
- D-Penicillamin-Bleisalz
- Reference substance name:
- Bleisalz der 2-Amino-3-mercapto-3-methylbuttersäure
- IUPAC Name:
- Bleisalz der 2-Amino-3-mercapto-3-methylbuttersäure
- Test material form:
- other: solid
- Details on test material:
- - Analytical purity: >99.0%
- Lot/batch No.: 120595
- Storage condition of test material: keine besonderen Maßnahmen
- Charakterisierung: graugelbes Pulver, charakteristischer Geruch
- Summenformel: C5H9NO2PbS
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge : Gemeinschaftsklärwerk Bitterfeld-Wolfen
- Preparation of inoculum for exposure: aerob gehalten, dekantierter Überstand als Inokulum verwendet - Duration of test (contact time):
- 34 d
Initial test substance concentration
- Initial conc.:
- 5 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Test temperature: 20-23°C. Kurzzeitig traten Temperaturen bis 19°C auf.
- Inokulum-Konzentration: 0,1 mL Inokulum/L
- Continuous darkness: ja
TEST SYSTEM
- Culturing apparatus: Karlsruher Flaschen
- Number of culture flasks/concentration: 20
SAMPLING
- Sampling frequency: Sauerstoffmessung erfolgte unmittelbar nach dem Befüllen und anschließend mindestens alle 4 Tage bis Tag 21, danach einmal pro Woche
Reference substance
- Reference substance:
- acetic acid, sodium salt
- Remarks:
- <90%
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 34 d
BOD5 / COD results
- Results with reference substance:
- 86% Abbau nach 3 Tagen, 90% nach 6 Tagen
Any other information on results incl. tables
Abbau der Prüfsubstanz:
Tag |
Durchschnittl. Abbau (%) |
3 |
3 |
6 |
3 |
10 |
2 |
14 |
0 |
17 |
2 |
21 |
0 |
28 |
5 |
34 |
0 |
Das Kriterium für leichte biologische Abbaubarkeit (60% Abbau am Ende des 10- Tage - Fensters) wurde nicht erfüllt.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- D-Penicillamin-Bleisalz wurde im Geschlossenen Flaschentest nach EU C.4-E nach 34 Tagen nicht abgebaut. Die Testbubstanz ist deshalb als biologisch nicht leicht abbaubar einzustufen.
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