1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives (upper limit: 41% w/w; typical concentration: 38% w/w)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Well conducted GLP study according to OECD Guideline 105

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Water solubility:

19.6 mg/L

Temp.:

20 °C

pH:

6

Remarks on result:

other: Constituent 1

Water solubility:

5.5 mg/L

Temp.:

20 °C

pH:

6

Remarks on result:

other: Constituent 2

Water solubility:

1.2 mg/L

Temp.:

20 °C

pH:

6

Remarks on result:

other: Constituent 3

Details on results:

The determined results for water solubility of the three main constituents are an average value for the three time points 24, 48 and 72 hours. In the overview below the result are given as determined concentration and converted using the composition data of the determined constituents, as given in sponsor info (AkzoNobel, 2014).

Average results

	Determined conc.	Converted conc.
	mg/L	mg/L
Constituent 1	19.6	3.1
Constituent 2	5.5	0.8
Constituent 3	1.2	0.06

Indivual results

Results preliminary test

Replicate	Constituent 1	Constituent 2	Constituent 3
	determined concentration	determined concentration	determined concentration
	mg/L	mg/L	mg/L
1	15.8	5.4	1.7
2	15.3	5.3	1.8
Average	15.6	5.3	1.7

Results definitive test, constituent 1

	Concentration
Time	I	II	Average	Difference
hr	mg/L	mg/L	mg/L	%
24	19.1	19.2	19.2
48	20.6	20.5	20.5	7.0
72	18.3	19.6	19.0	-7.6
Average			19.6
Converted			3.1

 

Results definitive test, constituent 2

	Concentration
Time	I	II	Average	Difference
hr	mg/L	mg/L	mg/L	%
24	5.4	5.4	5.4
48	5.9	5.9	5.9	8.9
72	4.9	5.3	5.1	-13.3
Average			5.5
Converted			0.8

 

Results definitive test, constituent 3

	Concentration
Time	I	II	Average	Difference
hr	mg/L	mg/L	mg/L	%
24	1.2	1.1	1.1
48	1.3	1.2	1.3	11.9
72	1.2	1.1	1.2	-8.3
Average			1.2
Converted			0.06

Conclusions:

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The purpose of this study was to determine the solubility of the test substance in water, complying with the OECD Guideline No. 105.

The test substance consisted of several constituents of which the three main constituents, based on percentages, were considered to be representative for the test substance (AkzoNobel, 2014).

The determined results for water solubility of the three main constituents are an average value for the three time points 24, 48 and 72 hours. In the overview below the result are given as determined concentration and converted using the composition data of the determined constituents, as given in sponsor info (AkzoNobel, 2014).

Determined conc. Converted conc.
mg/L mg/L
Constituent 1 19.6 3.1
Constituent 2 5.5 0.8
Constituent 3 1.2 0.06

Executive summary:

Well described GLP study, carried out according to OECD guideline.

The water solubility of the test substance was determined to be in the range 1.2 to 19.6 mg/l for the 3 tested constituents. Converted results using the composition data of the determined constituents ranged from 0.06 to 3.1 mg/L

Description of key information

The water solubility of the main organic peroxide consitutents of Trigonox 501-CS40 range from 1.2 - 19.6 mg/L @ 20 oC

Key value for chemical safety assessment

Water solubility:

19.6 mg/L

at the temperature of:

20 °C