Registration Dossier
Registration Dossier
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EC number: 219-210-0 | CAS number: 2387-03-3
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Classification of 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone for effects in the environment
In determining the classification appropriate to 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.
Persistence
Available data indicates that 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is not persistent in the aquatic and soil environment. However, its persistent characteristic is only observed in the sediment compartment. Hence it has been concluded that 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is persistent in nature.
Thus, 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is classified as a persistent chemical (P) but not very persistent (not vP) since only estimated half-life values for the same are available.
Potential to accumulate
Bioaccumulation (BCF) value of the substance 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone was calculated using the software BCFBAF (v3.01).The estimated bioconcentration factor (BCF) for 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is 4989 L/kg, that exceeds the bioconcentration threshold of 2000 but is less than 5000. Thus it is concluded that 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is expected to bioaccumulate in the food chain.
Thus, 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone satisfies the criterion for classification as bioaccumulative (B) but not very bioaccumulative (not vB) .
Toxicity
The lowest LC50 value is found to be 2.74 mg/l for algae which is higher than 0.01 mg/l. In addition, the EC50 value for aquatic invertebrates is determined to be > 100 mg/L. Thus based on these values, it can be concluded that 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is is not toxic for marine/ freshwater organisms as per the criteria set out in Annex XIII.
In addition to aquatic toxicity, the substance, 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone, is not classified as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) according to CLP (Regulation (EC) No 1272/2008) and there is no evidence of chronic toxicity, as identified by the classifications STOT (repeated exposure) according to Regulation (EC) No 1272/2008.
Thus, 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone does not meet the Annex XIII criterion for classification as toxic (T).
Thus, in accordance with the requirements of Annex XIII; it can be inferred that 2-hydroxynaphthalene-1-carbaldehyde [(2-hydroxy-1-naphthyl)methylene]hydrazone is a not a PBT (including vPvB) substance.
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