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EC number: 227-678-2 | CAS number: 5932-68-3
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 February - 22 April, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. Test substance is adequately specified with isomer purity. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- UK GLP compliance programme (inspected on 05 February 2014 / signed on 07 October 2015)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 1 Pa
- Remarks on result:
- other: interpolated
- Conclusions:
- Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), < 500 Pa).
- Executive summary:
The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline by an effusion method using a vapour pressure balance. Two definitive runs were performed between temperatures of 20 and 53 °C. Vapour pressure at 25 °C was interpolated from the regressions.
The runs yielded a mean vapour pressure value at 25 ºC of 1.0 Pa.
The vapour pressure of the test item has been determined to be 1.0 Pa at 25 °C.
Reference
Run 1
Correlation (r): -0.9895
Slope: -4097
Intercept: 13.79
Vp (Pa) at 25 °C: 1.11
Run 2
Correlation (r): -0.9952
Slope: -4236
Intercept: 14.19
Vp (Pa) at 25 °C: 0.965
The runs yielded a mean vapour pressure value at 25 ºC of 1.0 Pa.
Description of key information
Low volatility.
Key value for chemical safety assessment
- Vapour pressure:
- 1 Pa
- at the temperature of:
- 25 °C
Additional information
A fully reliable experimental study, conducted according to a recognized OECD/EU method, is available. It is considered as a key study. The result is retained as key data.
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