4-Piperidinecarboxylic acid, hydrochloride (1:1)

Auto flammability

Administrative data

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

26 August - 22 December 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2016

Report date:

2016

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

4-piperidinecarboxylic acid hydrochloride

EC Number:

611-901-9

Cas Number:

5984-56-5

Molecular formula:

C6H11NO2.HCl

IUPAC Name:

4-piperidinecarboxylic acid hydrochloride

Test material form:

solid: particulate/powder

Details on test material:

- Name of test material (as cited in study reports): JNJ-150098-AAC (T001310)
- Physical state: solid
- Appearance white powder

Specific details on test material used for the study:

- Batch n°: I14KB4913
- Analytical purity: 97.4% (base titration)
- Expiration date: 23 November 2020 (retest date)
- Storage condition: at room temperature

Results and discussion

Relative self-ignition temperature (solids)

Key result

Remarks on result:

no self-ignition observed up to the melting point

Any other information on results incl. tables

A strong exothermic effect of the test item was observed. The temperature of the test item reached 400°C at an oven temperature of 390°C. It demonstrated that the self-ignition temperature of the test item is 390°C.

After the experiment, the test item had turned into a black/brown residue and was partially collected in a container that was placed below the cube. It indicated that the test item had expanded, decomposed and/or reacted during the experiment.

At temperatures below 390°C the sample temperature followed the oven temperature. No self-ignition was observed up to the melting point (298.2°C).

Applicant's summary and conclusion

Conclusions:

In the EC A.16 test performed, the self-ignition temperature of JNJ-150098-AAC (T001310) was determined to be 390°C. At lower oven temperatures, the sample temperature followed the oven temperature. Up to the melting point (298.2°C) no self-ignition was observed.