Registration Dossier
Registration Dossier
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EC number: 207-079-2 | CAS number: 431-89-0
Endpoint summary
Administrative data
Description of key information
In accordance to section 2 of REACH Annex XI, skin and eye irritation studies do not need to be conducted as the substance is a gas.
Key value for chemical safety assessment
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
The gaseous nature of 1,1,1,2,3,3,3 -heptafluoropropane precludes the conduct of conventional skin and eye irritation tests in animals.
No signs of respiratory tract irritation were observed in the available acute and repeated dose studies, indicating that the substance is not a respiratory tract irritant.
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
Based on the available negative eye irritation study and due to gaseous nature of the substance, classification of 1,1,1,2,3,3,3 -heptafluoropropane for skin and eye irritation is not applicable according to EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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