Bis(2,3-epoxypropyl) cyclohex-4-ene-1,2-dicarboxylate

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental strating date: 16 August 2014 and Experimental Completion date: 19 August 2014.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

23 March 2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: OECD Guidelines for Testing of Chemicals

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: Commission Regulation (EC) N°440/2008 (as amended) of 30 May 2008, Part A: Methods for the determination of physico-chemical properties

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

other: Balance method

Key result

Temp.:

25 °C

Vapour pressure:

0 Pa

Remarks on result:

other: 5 runs were performed and the mean gave this Vapor pressure value.

Summary of vapor pressure Data.

Run	Log10 (Vp(25°C))
2	-3.91
3	-4.02
4	-3.95
5	-4.03
Mean	-3.98
Vapor pressure	1.1 x 10E-4 Pa

The test item dd not change in appearance under the conditions used in the determination.

Discussion:

The un-shaded points on the garphs have not been used in the data analysis. The omission of these points is justified due to the fact that tipically, the first few points on a run can be erroneous due to the system undergoing a process of settling.

A total of 5 runs were completed for the main sequence. Equilibrium with regard to vapor pressure was assessed to have been reached over the final four runs. Thus the final four runs have been used to calculate the definitive vapor pressure value for the test item.

In conclusion, the vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C

Results:

Recorded temperatures, mass difference and the resulting calculated values of vapor pressure are shown in the following table:

Run 2

Temperature °C	Temperature K	Reciprocal Temperature (K-1)	Mass difference (microgr)	Mass difference (kg)	Vapor pressure (Pa)	Log10 Vp
103	376.15	0.002658514	194.69	1.947 E-07	0.270279599	-0.568186734
104	377.15	0.002651465	208.07	2.081 E-07	0.288854467	-0.539320912
105	378.15	0.002644453	237.33	2.373 E-07	0.32974844	-0.482177739
106	379.15	0.002637479	252.90	2.529 E-07	0.351089993	-0.454581549
107	380.15	0.002630541	266.98	2.670 E-07	0.370636640	-0.431051650
108	381.15	0.002623639	286.95	2.870 E-07	0.398360116	-0.399724150
109	382.15	0.002616774	317.80	3.178 E-07	0.441187820	-0.355376486
110	383.15	0.002609944	330.88	3.309 E-07	0.459346211	-0.337859862

A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 2 gives the following statistical data using an unweighted least squares treatment

Slope: -4.81 x 10E3

Standard erro in slope: 203

Intercept: 12.2

Standard error in intercept: 0.536

The results obtained indicate the following vapor pressure relationship:

Log10 (Vp(Pa)) = -4.81 x 10E3/temp (K) +12.2

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -3.91.

Run 3

Temperature °C	Temperature K	Reciprocal Temperature (K-1)	Mass difference (microgr)	Mass difference (kg)	Vapor pressure (Pa)	Log10 Vp
103	376.15	0.002658514	202.58	2.026 E-07	0.281232941	-0.550933812
104	377.15	0.002651465	214.36	2.144 E-07	0.297586599	-0.526386630
105	378.15	0.002644453	226.84	2.268 E-07	0.314912036	-0.501810740
106	379.15	0.002637479	243.22	2.432 E-07	0.337651673	-0.471531095
107	380.15	0.002630541	264.49	2.645 E-07	0.367179882	-0.435121022
108	381.15	0.002623639	294.54	2.945 E-07	0.408896981	-0.388386096
109	382.15	0.002616774	321.80	3.218 E-07	0.446740845	-0.349944339
110	383.15	0.002609944	347.36	3.474 E-07	0.482224673	-0.316750573

A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 3 gives the following statistical data using an unweighted least squares treatment

Slope: -4.97 x 10E3

Standard erro in slope: 216

Intercept: 12.6

Standard error in intercept: 0.570

The results obtained indicate the following vapor pressure relationship:

Log10 (Vp(Pa)) = -4.97 x 10E3/temp (K) +12.6

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -4.02.

Run 4

Temperature °C	Temperature K	Reciprocal Temperature (K-1)	Mass difference (microgr)	Mass difference (kg)	Vapor pressure (Pa)	Log10 Vp
103	376.15	0.002658514	196.09	1.961 E-07	0.272223158	-0.5
104	377.15	0.002651465	216.06	2.161 E-07	0.299946634	-0.52
105	378.15	0.002644453	231.37	2.313 E-07	0.321159189	-0.
106	379.15	0.002637479	248.61	3.486 E-07	0.345134374	-0.4
107	380.15	0.002630541	264.68	2.647 E-07	0.367443651	-0.43
108	381.15	0.002623639	292.14	2.921 E-07	0.405565166	-0.3
109	382.15	0.002616774	311.21	3.112 E-07	0.432039212	-0.3
110	383.15	0.002609944	344.66	3.447 E-07	0.478476381	-0.3

A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 4 gives the following statistical data using an unweighted least squares treatment

Slope: -4.77 x 10E3

Standard erro in slope: 118

Intercept: 12.4

Standard error in intercept: 0.311

The results obtained indicate the following vapor pressure relationship:

Log10 (Vp(Pa)) = -4.87 x 10E3/temp (K) +12.4

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -3.95.

Run 5

Temperature °C	Temperature K	Reciprocal Temperature (K-1)	Mass difference (microgr)	Mass difference (kg)	Vapor pressure (Pa)	Log10 Vp
103	376.15	0.002658514	191.10	1.911 E-07	0.265295760	-0.576269692
104	377.15	0.002651465	200.49	2.005 E-07	0.278331485	-0.555437663
105	378.15	0.002644453	215.36	2.154 E-07	0.298974855	-0.524365336
106	379.15	0.002637479	237.03	2.370 E-07	0.329058367	-0.482727062
107	380.15	0.002630541	252.60	2.526 E-07	0.350673516	-0.455097033
108	381.15	0.002623639	279.36	2.794 E-07	0.387823252	-0.411366157
109	382.15	0.002616774	299.43	2.994 E-07	0.415685554	-0.381235068
110	383.15	0.002609944	328.98	3.290 E-07	0.456708524	-0.340360882

A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 5 gives the following statistical data using an unweighted least squares treatment

Slope: -4.96 x 10E3

Standard erro in slope: 148

Intercept: 12.6

Standard error in intercept: 0.390

The results obtained indicate the following vapor pressure relationship:

Log10 (Vp(Pa)) = -4.97 x 10E3/temp (K) +12.6

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -4.03.

Conclusions:

The vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C

Executive summary:

The vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C, using the vapor pressure of Commission Regulation (EC) N° 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.

Key value for chemical safety assessment

Vapour pressure:

0 Pa

at the temperature of:

25 °C

Additional information

The vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C, using the vapor pressure of Commission Regulation (EC) N° 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.