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EC number: 244-435-6 | CAS number: 21544-03-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental strating date: 16 August 2014 and Experimental Completion date: 19 August 2014.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 23 March 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guidelines for Testing of Chemicals
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: Commission Regulation (EC) N°440/2008 (as amended) of 30 May 2008, Part A: Methods for the determination of physico-chemical properties
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Balance method
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: 5 runs were performed and the mean gave this Vapor pressure value.
- Conclusions:
- The vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C
- Executive summary:
The vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C, using the vapor pressure of Commission Regulation (EC) N° 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Reference
Summary of vapor pressure Data.
Run | Log10 (Vp(25°C)) |
2 | -3.91 |
3 | -4.02 |
4 | -3.95 |
5 | -4.03 |
Mean | -3.98 |
Vapor pressure | 1.1 x 10E-4 Pa |
The test item dd not change in appearance under the conditions used in the determination.
Discussion:
The un-shaded points on the garphs have not been used in the data analysis. The omission of these points is justified due to the fact that tipically, the first few points on a run can be erroneous due to the system undergoing a process of settling.
A total of 5 runs were completed for the main sequence. Equilibrium with regard to vapor pressure was assessed to have been reached over the final four runs. Thus the final four runs have been used to calculate the definitive vapor pressure value for the test item.
In conclusion, the vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C
Results:
Recorded temperatures, mass difference and the resulting calculated values of vapor pressure are shown in the following table:
Run 2
Temperature °C | Temperature K | Reciprocal Temperature (K-1) | Mass difference (microgr) | Mass difference (kg) | Vapor pressure (Pa) | Log10 Vp |
103 | 376.15 | 0.002658514 | 194.69 | 1.947 E-07 | 0.270279599 | -0.568186734 |
104 | 377.15 | 0.002651465 | 208.07 | 2.081 E-07 | 0.288854467 | -0.539320912 |
105 | 378.15 | 0.002644453 | 237.33 | 2.373 E-07 | 0.32974844 | -0.482177739 |
106 | 379.15 | 0.002637479 | 252.90 | 2.529 E-07 | 0.351089993 | -0.454581549 |
107 | 380.15 | 0.002630541 | 266.98 | 2.670 E-07 | 0.370636640 | -0.431051650 |
108 | 381.15 | 0.002623639 | 286.95 | 2.870 E-07 | 0.398360116 | -0.399724150 |
109 | 382.15 | 0.002616774 | 317.80 | 3.178 E-07 | 0.441187820 | -0.355376486 |
110 | 383.15 | 0.002609944 | 330.88 | 3.309 E-07 | 0.459346211 | -0.337859862 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 2 gives the following statistical data using an unweighted least squares treatment
Slope: -4.81 x 10E3
Standard erro in slope: 203
Intercept: 12.2
Standard error in intercept: 0.536
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp(Pa)) = -4.81 x 10E3/temp (K) +12.2
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -3.91.
Run 3
Temperature °C | Temperature K | Reciprocal Temperature (K-1) | Mass difference (microgr) | Mass difference (kg) | Vapor pressure (Pa) | Log10 Vp |
103 | 376.15 | 0.002658514 | 202.58 | 2.026 E-07 | 0.281232941 | -0.550933812 |
104 | 377.15 | 0.002651465 | 214.36 | 2.144 E-07 | 0.297586599 | -0.526386630 |
105 | 378.15 | 0.002644453 | 226.84 | 2.268 E-07 | 0.314912036 | -0.501810740 |
106 | 379.15 | 0.002637479 | 243.22 | 2.432 E-07 | 0.337651673 | -0.471531095 |
107 | 380.15 | 0.002630541 | 264.49 | 2.645 E-07 | 0.367179882 | -0.435121022 |
108 | 381.15 | 0.002623639 | 294.54 | 2.945 E-07 | 0.408896981 | -0.388386096 |
109 | 382.15 | 0.002616774 | 321.80 | 3.218 E-07 | 0.446740845 | -0.349944339 |
110 | 383.15 | 0.002609944 | 347.36 | 3.474 E-07 | 0.482224673 | -0.316750573 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 3 gives the following statistical data using an unweighted least squares treatment
Slope: -4.97 x 10E3
Standard erro in slope: 216
Intercept: 12.6
Standard error in intercept: 0.570
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp(Pa)) = -4.97 x 10E3/temp (K) +12.6
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -4.02.
Run 4
Temperature °C | Temperature K | Reciprocal Temperature (K-1) | Mass difference (microgr) | Mass difference (kg) | Vapor pressure (Pa) | Log10 Vp |
103 | 376.15 | 0.002658514 | 196.09 | 1.961 E-07 | 0.272223158 | -0.5 |
104 | 377.15 | 0.002651465 | 216.06 | 2.161 E-07 | 0.299946634 | -0.52 |
105 | 378.15 | 0.002644453 | 231.37 | 2.313 E-07 | 0.321159189 | -0. |
106 | 379.15 | 0.002637479 | 248.61 | 3.486 E-07 | 0.345134374 | -0.4 |
107 | 380.15 | 0.002630541 | 264.68 | 2.647 E-07 | 0.367443651 | -0.43 |
108 | 381.15 | 0.002623639 | 292.14 | 2.921 E-07 | 0.405565166 | -0.3 |
109 | 382.15 | 0.002616774 | 311.21 | 3.112 E-07 | 0.432039212 | -0.3 |
110 | 383.15 | 0.002609944 | 344.66 | 3.447 E-07 | 0.478476381 | -0.3 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 4 gives the following statistical data using an unweighted least squares treatment
Slope: -4.77 x 10E3
Standard erro in slope: 118
Intercept: 12.4
Standard error in intercept: 0.311
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp(Pa)) = -4.87 x 10E3/temp (K) +12.4
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -3.95.
Run 5
Temperature °C | Temperature K | Reciprocal Temperature (K-1) | Mass difference (microgr) | Mass difference (kg) | Vapor pressure (Pa) | Log10 Vp |
103 | 376.15 | 0.002658514 | 191.10 | 1.911 E-07 | 0.265295760 | -0.576269692 |
104 | 377.15 | 0.002651465 | 200.49 | 2.005 E-07 | 0.278331485 | -0.555437663 |
105 | 378.15 | 0.002644453 | 215.36 | 2.154 E-07 | 0.298974855 | -0.524365336 |
106 | 379.15 | 0.002637479 | 237.03 | 2.370 E-07 | 0.329058367 | -0.482727062 |
107 | 380.15 | 0.002630541 | 252.60 | 2.526 E-07 | 0.350673516 | -0.455097033 |
108 | 381.15 | 0.002623639 | 279.36 | 2.794 E-07 | 0.387823252 | -0.411366157 |
109 | 382.15 | 0.002616774 | 299.43 | 2.994 E-07 | 0.415685554 | -0.381235068 |
110 | 383.15 | 0.002609944 | 328.98 | 3.290 E-07 | 0.456708524 | -0.340360882 |
A plot of Log10 (vapor pressure (Pa)) versus reciprocal temperature (1/T (K)) for Run 5 gives the following statistical data using an unweighted least squares treatment
Slope: -4.96 x 10E3
Standard erro in slope: 148
Intercept: 12.6
Standard error in intercept: 0.390
The results obtained indicate the following vapor pressure relationship:
Log10 (Vp(Pa)) = -4.97 x 10E3/temp (K) +12.6
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -4.03.
Description of key information
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
The vapor pressure of the test item has been determined to be 1.1 x10E-4 Pa at 25°C, using the vapor pressure of Commission Regulation (EC) N° 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
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