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Description of key information

1,2 pentanediol is  non mutagenic in the Ames test (OECD 471) and the mouse lymphoma test (L5178Y TK +/-; OECD476). No clastogenicity was found in a chromosomal aberration test (OECD 473). Therefore 1,2 pentanediol is considered to be clearly non mutagenic. According to column 2 Annex Xit is not necessary to conduct a carcinogenicity study therefore. Beyond this there are no hints for a possible secondary cancer mechanism. 1,2 pentane diol therefore is expected to be non carcinogenic.

Key value for chemical safety assessment

Justification for classification or non-classification

 Classification for carcinogenicity is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.

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