Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
publication
Title:
Industrial Hygien and Toxicology: Volume II: Toxicology 2nd ed. New York
Author:
Patty F.
Year:
1963
Bibliographic source:
Interscience Publishers p. 1824

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Propiolactone
EC Number:
200-340-1
EC Name:
Propiolactone
Cas Number:
57-57-8
Molecular formula:
C3H4O2
IUPAC Name:
oxetan-2-one

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 50 - < 100 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

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