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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
Internal reference PNT 2090143 DOC/006 Ed 11. Anexe VII
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
855.3 µm
Geometric standard deviation:
507.9
Key result
Percentile:
D10
Mean:
226.6 µm
Remarks on result:
other: std. dev. not measured
Key result
Percentile:
D50
Mean:
789.2 µm
Remarks on result:
other: std. dev. not measured
Key result
Percentile:
D90
Mean:
1 621 µm
Remarks on result:
other: std. dev. not measured
Conclusions:
The mass median diameter of the particles is 855.3 μm

Description of key information

The particles size determination is done by means of laser diffraction analysis.

The mass median diameter of the particles determined by laser diffraction analysis is 855.2 μm: the powder is considered to be of low/medium volatility.

Additional information

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