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EC number: 257-573-7 | CAS number: 51981-21-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
The aquatic hazard assessment of GLDA-H4 reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance. The substance is readily biodegradable and has a very low log Kow, this indicates that the substance will not be persistent or bioaccumulative. There are no further indications that the substance may be hazardous to the environment.
Based on the expected use, the effect of GLDA-Na4 (CAS No. 51981 -21 -6) (Batch no.FC-C11836) on three terrestrial species has been evaluated.
The effect of GLDA-Na4 on mortality, growth and the reproductive potential of the earthworm species Eisenia fetida (Annelida, Lumbricidae) according to OECD Guideline 222 (2004). The NOEC based on Geometric mean measured concentration concerning growth and reproduction was determined to be 117.8 mg a.i./kg soil DW. No ECx-values were calculated since no statistically significant mortality and reduction of body weight gain or reproduction occurred.
The phytotoxicity of GLDA-Na4 to three terrestrial plant species was determined in a seedling emergence and seedling growth test over a period of 21 days according to OECD 208 (July 2006). Test systems comprised one monocotyledons (oats, Poaceae), and two dicotyledons (rape, Brassicaceae; soybean, Leguminosae).
The toxic effects of the test item were determined on day 7, 14 and 21 by visual observations (number of emerged seedlings and phytotoxic effects) and on day 21 by shoot height and shoot fresh weight determination.
The NOEC based on geometric mean measured concentration concerning shoot height, shoot fresh weight and seedling emergence was determined to be 358.2 mg a.i./kg dw.
The effects of GLDA-Na4 on the metabolic activity of soil micro-organisms were determined according to OECD Guideline 216 (2000).
The rates of nitrate formation were statistically significant higher in the geometric mean measured test item concentration 53.1 mg/kg DW compared to the untreated control after 7 and 28 days of exposure (Figure1). Consequently, there was no evidence that exposure to GLDA-Na4 inhibited the nitrogen transformation activity of soil microflora at the range of concentrations applied. The EC50 based on inhibition of nitrogen transformation processes could not be determined, as no inhibitory effects were observed at any test item concentration. The corresponding EC10 based on geometric mean was≥25.22 mg a.i./kg soil dry weight, this concentration is equivalent to the nominal concentration of 1000 mg/kg soil dry weight.
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